Watch: First Trailer For 'The Skeleton Twins' Starring Kristen Wiig & Bill Hader

The Skeleton TwinsWhile Kristen Wiig has already played her breakout role in "Bridesmaids," and has used that opportunity to forge her own path in Hollywood, including lining up a new directorial gig, we’ve been waiting for her "Saturday Night Live" co-star Bill Hader to get his shot. He’s certainly lined up no shortage of small roles in a number of movies (everything from "Superbad" to "The Disappearance Of Eleanor Rigby"), but in "The Skeleton Twins" he co-stars with Wiig with the pair leading the dramedy.

Premiering earlier this year at the Sundance Film Festival, the movie follows an estranged brother and sister, reunited after ten years, who face the various challenges in their lives. Craig Johnson ("True Adolescents") directs the film, which has a score from Nathan Larson, and while we had mixed feelings on the movie, we noted out of Park City that that the film "proves to be a fine showcase for Wiig and Hader, showing they are both capable of dramatic material."

"The Skeleton Twins" opens on September 19th. Poster via EW.

Skeleton Twins, poster